Ammonia → 1-(2,4-difluorophenyl)-1-(4-(4-carbamoylthiazol-2-yl)-thiophen-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethanol
Reaction equation
[CH3:33][OH:34].[F:1][c:2]1[c:3]([C:9]([CH2:10][n:11]2[n:12][cH:13][n:14][cH:15]2)([OH:16])[c:17]2[s:18][cH:19][c:20](-[c:22]3[s:23][cH:24][c:25]([C:27]([O:29][CH2:28][CH3:30])=[O:31])[n:26]3)[cH:21]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[NH3:32]>>[F:1][c:2]1[c:3]([C:9]([CH2:10][n:11]2[n:12][cH:13][n:14][cH:15]2)([OH:16])[c:17]2[s:18][cH:19][c:20](-[c:22]3[s:23][cH:24][c:25]([C:27](=[O:29])[NH2:32])[n:26]3)[cH:21]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-f9c8e9e708d64f5bbece48ef3086e6b8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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