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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 819110Generated: October 27, 2026

Tetrahydrofuran → 2-(3,4-Dichloro-phenyl)-3-[2-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-propionic acid methyl ester

https://huagongshe.com/reaction/819110

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-HCID 81646—
ReactantMethyl 2-(3,4-dichlorophenyl)acetateHCID 1268257—
ReactantDiisopropylamideHCID 5062348—
Reactant2-(2-Iodomethyl-cyclopentyloxy)-tetrahydropyranHCID 21958974—
Product2-(3,4-Dichloro-phenyl)-3-[2-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-propionic acid methyl esterHCID 67482133—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-cdc7f3bdf44447aa86a4ecd9d7d1a18a
Source noteTest data from https://doi.org/10.1039/C8SC04228D