Benzhydryl 2-chloroethyl ether → 1'-(2-Benzhydryloxyethyl)-1,3-dihydrospiro[isobenzofuran-1,4'-piperidine]-3-one
Reaction equation
[CH:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[O:29][CH2:30][CH2:31][Cl:32].[NH:1]1[CH2:2][CH2:3][C:4]2([O:5][C:6](=[O:13])[c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]32)[CH2:14][CH2:15]1>>[N:1]1([CH2:31][CH2:30][O:29][CH:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:2][CH2:3][C:4]2([O:5][C:6](=[O:13])[c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]32)[CH2:14][CH2:15]1Participants
3
Sources & evidence
- ORD record
- ord-2c70258b9ab6432c9bb0b034062c8d76
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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