2-Bromo-5-(trifluoromethyl)benzaldehyde → (6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

HRID 819126Notes

Reaction equation

HRID 819126 reaction equation
[Br:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][c:7]([C:10]([F:11])([F:12])[F:13])[cH:8][cH:9]1.[CH3:14][O:15][C:16]([CH2:17][c:18]1[cH:19][c:20]([B:25]2[O:26][C:27]([CH3:28])([CH3:29])[C:30]([CH3:31])([CH3:32])[O:33]2)[c:21]([F:24])[cH:22][cH:23]1)=[O:34]>>[c:2]1(-[c:20]2[cH:19][c:18]([CH2:17][C:16]([O:15][CH3:14])=[O:34])[cH:23][cH:22][c:21]2[F:24])[c:3]([CH:4]=[O:5])[cH:6][c:7]([C:10]([F:11])([F:12])[F:13])[cH:8][cH:9]1

Participants

3

Reactant 2

HCID 70180472-Bromo-5-(trifluoromethyl)benzaldehydeHCID 46739456Methyl 2-(4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate

Product 1

HCID 86633169(6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

Sources & evidence

ORD record
ord-4d8eac81405c423b91af1f2c91ac24a5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…