Bicarbonate Ion → 7-(6-Chloro-indole-1-sulfonyl)4,4-dimethyl-1,2,3,4-tetrahydro-isoquinoline

HRID 819520Notes

Reaction equation

HRID 819520 reaction equation
[C:29](=[O:30])([O-:31])[OH:32].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][n:8]([S:11](=[O:12])(=[O:13])[c:14]3[cH:15][cH:16][c:17]4[c:22]([cH:23]3)[CH2:21][N:20]([C:24](=[O:25])[CH3:26])[CH2:19][C:18]4([CH3:27])[CH3:28])[c:9]2[cH:10]1.[Na+:33]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][n:8]([S:11](=[O:12])(=[O:13])[c:14]3[cH:15][cH:16][c:17]4[c:22]([cH:23]3)[CH2:21][NH:20][CH2:19][C:18]4([CH3:27])[CH3:28])[c:9]2[cH:10]1

Participants

4

Reactant 3

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 225920261-[7-(6-Chloro-indole-1-sulfonyl)-4,4-dimethyl-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone

Product 1

HCID 101994437-(6-Chloro-indole-1-sulfonyl)4,4-dimethyl-1,2,3,4-tetrahydro-isoquinoline

Sources & evidence

ORD record
ord-756afb57eca745aba22a3c0435c4ebd9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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