3-Morpholino-1-propanol → N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide

HRID 819541Notes

Reaction equation

HRID 819541 reaction equation
[Cl:1][c:2]1[c:3](-[c:26]2[n:27][nH:28][cH:29][n:30]2)[c:4]([NH:7][C:8]([CH2:9][n:10]2[c:11](=[O:24])[cH:12][cH:13][c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][c:19]23)=[O:25])[s:5][cH:6]1.[O:31]1[CH2:32][CH2:33][N:34]([CH2:37][CH2:38][CH2:39][OH:40])[CH2:35][CH2:36]1>>[Cl:1][c:2]1[c:3](-[c:26]2[n:27][n:28]([CH2:39][CH2:38][CH2:37][N:34]3[CH2:33][CH2:32][O:31][CH2:36][CH2:35]3)[cH:29][n:30]2)[c:4]([NH:7][C:8]([CH2:9][n:10]2[c:11](=[O:24])[cH:12][cH:13][c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][c:19]23)=[O:25])[s:5][cH:6]1

Participants

3

Reactant 2

HCID 1995763-Morpholino-1-propanolHCID 178521249HCID 178521249, compound

Product 1

HCID 46869289N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide

Sources & evidence

ORD record
ord-6dd714ad60284aa28f238fab0b327309
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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