Pyridine → tetrahydro-1-(5-methylsulfinyl-1,3,4-thiadiazol-2-yl)-3-propargyl-6-cyclopropoxycarbonyloxy-2(1H)-pyrimidinone

HRID 819900Notes

Reaction equation

HRID 819900 reaction equation
[CH3:1][S:2](=[O:3])[c:4]1[n:5][n:6][c:7]([N:9]2[C:10](=[O:19])[N:11]([CH2:16][C:17]#[CH:18])[CH2:12][CH2:13][CH:14]2[OH:15])[s:8]1.[Cl:20][C:21](=[O:22])[O:23][CH:24]1[CH2:25][CH2:26]1.[cH:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1>>[CH3:1][S:2](=[O:3])[c:4]1[n:5][n:6][c:7]([N:9]2[C:10](=[O:19])[N:11]([CH2:16][C:17]#[CH:18])[CH2:12][CH2:13][CH:14]2[O:15][C:21](=[O:22])[O:23][CH:24]2[CH2:25][CH2:26]2)[s:8]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 14593404Cyclopropyl chloroformateHCID 21400073tetrahydro-1-(5-methylsulfinyl-1,3,4-thiadiazol-2-yl)-3-propargyl-6-hydroxy-2(1H)-pyrimidinone

Product 1

HCID 21418696tetrahydro-1-(5-methylsulfinyl-1,3,4-thiadiazol-2-yl)-3-propargyl-6-cyclopropoxycarbonyloxy-2(1H)-pyrimidinone

Sources & evidence

ORD record
ord-f308210ac872436a91570ec1829d2f8e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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