HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyanogen Bromide → 7-(3,5-dimethyl-4-isoxazolyl)-1-[1-methyl-2-(methyloxy)ethyl]-8-(methyloxy)-1H-imidazo[4,5-c]quinolin-2-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyanogen Bromide | HCID 10476 | — |
| Edukt | 7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-N4-(1-methoxypropan-2-yl)quinoline-3,4-diamine | HCID 70980379 | — |
| Produkt | 7-(3,5-dimethyl-4-isoxazolyl)-1-[1-methyl-2-(methyloxy)ethyl]-8-(methyloxy)-1H-imidazo[4,5-c]quinolin-2-amine | HCID 66571283 | 30% |
Reaktionsschritte
From 7-(3,5-dimethyl-4-isoxazolyl)-N4-[1-methyl-2-(methyloxy)ethyl]-6-(methyloxy)-3,4-quinolinediamine (for a preparation see Intermediate 17) (70 mg) and cyanogen bromide (20 mg) to give the title compound as beige solid (23 mg, 30%). LCMS (formate) Rt 0.67 min, MH+ 382
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846709B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-bea8b8272a304a1e8f27188dacf342be |
| Quellennotiz | uspto-grants-2014_09 |