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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 82005Generated: October 26, 2026

2-Morpholinoethyl isothiocyanate → HCID 66571342, compound

https://huagongshe.com/reaction/82005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Morpholinoethyl isothiocyanateHCID 143957—
Reactant7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-N4-(1-methoxypropan-2-yl)quinoline-3,4-diamineHCID 70980379—
ProductHCID 66571342HCID 6657134246%

Reaction Steps

From 7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-N4-(1-methoxypropan-2-yl)quinoline-3,4-diamine (for a preparation see Intermediate 19) (70 mg) and 4-(2-isothiocyanatoethyl)morpholine (50 mg) to give the title compound as beige solid (45 mg, 46%). LCMS (formate) Rt 0.56 min, MH+ 495

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846709B2
Source datasetuspto-grants-2014_09
ORD IDord-070023a274514322b56f86af4b60a8e3
Source noteuspto-grants-2014_09