5-Bromo-3-[(2,6-difluorobenzyl)oxy]pyridine-2-amine → Ethyl 2-[4-[6-amino-5-[(2,6-difluorophenyl)methoxy]-3-pyridinyl]phenoxy]acetate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([O:9][CH2:10][c:11]2[c:12]([F:18])[cH:13][cH:14][cH:15][c:16]2[F:17])[c:5]([NH2:8])[n:6][cH:7]1.[CH2:19]([CH3:20])[O:21][C:22]([CH2:23][O:24][c:25]1[cH:26][cH:27][c:28]([CH:31]2[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]2)[cH:29][cH:30]1)=[O:40]>>[c:2]1(-[c:28]2[cH:27][cH:26][c:25]([O:24][CH2:23][C:22]([O:21][CH2:19][CH3:20])=[O:40])[cH:30][cH:29]2)[cH:3][c:4]([O:9][CH2:10][c:11]2[c:12]([F:18])[cH:13][cH:14][cH:15][c:16]2[F:17])[c:5]([NH2:8])[n:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-60823787a2dc45dc9d62115efad0de95
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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