2-Quinolinecarboxaldehyde → 4-Quinolin-2-ylmethyl-piperazine-1-carboxylic acid (4-fluoro-phenyl)-amide
Reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:6][cH:7]1.[n:17]1[c:18]([CH:27]=[O:28])[cH:19][cH:20][c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]12>>[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([CH2:27][c:18]3[n:17][c:26]4[c:21]([cH:20][cH:19]3)[cH:22][cH:23][cH:24][cH:25]4)[CH2:15][CH2:16]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-26dad050d1b84ecbb6387c86d16c6c2e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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