Bromide ion → 2-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphth-2-yl)ethynyl]-5-(1-hydroxypropyl)pyridine
Reaction equation
[Br-:1].[CH2:2]([CH3:3])[Mg+:4].[CH3:5][C:6]1([CH3:28])[c:7]2[cH:8][cH:9][c:10]([C:18]#[C:19][c:20]3[n:21][cH:22][c:23]([CH:26]=[O:27])[cH:24][cH:25]3)[cH:11][c:12]2[C:13]([CH3:16])([CH3:17])[CH2:14][CH2:15]1>>[CH2:2]([CH3:3])[CH:26]([c:23]1[cH:22][n:21][c:20]([C:19]#[C:18][c:10]2[cH:9][cH:8][c:7]3[c:12]([cH:11]2)[C:13]([CH3:16])([CH3:17])[CH2:14][CH2:15][C:6]3([CH3:5])[CH3:28])[cH:25][cH:24]1)[OH:27]Participants
4
Sources & evidence
- ORD record
- ord-5f312013164f483dac40af4e718715c1
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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