2-Bromo-N-(5-chloro-2-pyridinyl)acetamide → 1-[(5-Chloro-pyridin-2-ylcarbamoyl)-methyl]-2-(1-cyclopropyl-piperidin-4-ylcarbamoyl)-1H-benzoimidazole-4-carboxylic acid methyl ester
Reaction equation
[Br:26][CH2:27][C:28](=[O:29])[NH:30][c:31]1[n:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][cH:8][c:9]2[nH:10][c:11]([C:14]([NH:15][CH:16]3[CH2:17][CH2:18][N:19]([CH:22]4[CH2:23][CH2:24]4)[CH2:20][CH2:21]3)=[O:25])[n:12][c:13]12>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][cH:8][c:9]2[n:10]([CH2:27][C:28](=[O:29])[NH:30][c:31]3[n:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]3)[c:11]([C:14]([NH:15][CH:16]3[CH2:17][CH2:18][N:19]([CH:22]4[CH2:23][CH2:24]4)[CH2:20][CH2:21]3)=[O:25])[n:12][c:13]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ad6b1546b0a64c61969c2c40a8027588
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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