Bicarbonate Ion → Ethyl 6-bromo-2-aminobenzo[b]thiophene-3-carboxylate

HRID 820270Notes

Reaction equation

HRID 820270 reaction equation
[Br:16][N:17]1[C:18](=[O:19])[CH2:20][CH2:21][C:22]1=[O:23].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]2[c:8]([s:9][c:10]1[NH2:11])[cH:12][cH:13][cH:14][cH:15]2.[Cl:29][CH:30]([Cl:31])[Cl:32].[Na+:28].[O-:24][C:25]([OH:26])=[O:27]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]2[c:8]([s:9][c:10]1[NH2:11])[cH:12][c:13]([Br:16])[cH:14][cH:15]2

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6212ChloroformHCID 67184N-bromobutanimideHCID 699464Ethyl 2-amino-1-benzothiophene-3-carboxylate

Product 1

HCID 18422163Ethyl 6-bromo-2-aminobenzo[b]thiophene-3-carboxylate

Sources & evidence

ORD record
ord-b740c0ca5343455c9acc9b996b68aa1e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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