5-Chloromethyl-4-cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidine → 3-{4-[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-ylmethoxy]-2-methyl-phenyl}-propionic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][c:7]1[c:8]([CH3:14])[cH:9][c:10]([OH:13])[cH:11][cH:12]1)=[O:15].[Cl:16][CH2:17][c:18]1[c:19]([CH:34]2[CH2:35][CH2:36]2)[n:20][c:21](-[c:24]2[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]2)[n:22][cH:23]1>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][c:7]1[c:8]([CH3:14])[cH:9][c:10]([O:13][CH2:17][c:18]2[c:19]([CH:34]3[CH2:35][CH2:36]3)[n:20][c:21](-[c:24]3[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]3)[n:22][cH:23]2)[cH:11][cH:12]1)=[O:15]Participants
3
Sources & evidence
- ORD record
- ord-a375e70fc5f6478695288d641c103539
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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