1-(1,1-Dimethyl-2-pyrrolidin-1-yl-ethyl)4-nitro-1H-imidazole → 2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)imidazol-4-yl]-2-phenylacetamide

HRID 820367Notes

Reaction equation

HRID 820367 reaction equation
[CH3:1][C:2]([CH2:3][N:4]1[CH2:5][CH2:6][CH2:7][CH2:8]1)([CH3:9])[n:10]1[cH:11][n:12][c:13]([N+:15]([O-:16])=[O:17])[cH:14]1.[F:18][c:19]1[cH:20][c:21]([CH2:26][C:27](=[O:28])[NH:29][CH:30]([C:31](=[O:32])[OH:33])[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:22][c:23]([F:25])[cH:24]1>>[CH3:1][C:2]([CH2:3][N:4]1[CH2:5][CH2:6][CH2:7][CH2:8]1)([CH3:9])[n:10]1[cH:11][n:12][c:13]([NH:15][C:31]([CH:30]([NH:29][C:27]([CH2:26][c:21]2[cH:20][c:19]([F:18])[cH:24][c:23]([F:25])[cH:22]2)=[O:28])[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)=[O:32])[cH:14]1

Participants

3

Reactant 2

HCID 671651351-(1,1-Dimethyl-2-pyrrolidin-1-yl-ethyl)4-nitro-1H-imidazoleHCID 775031002-[[2-(3,5-Difluorophenyl)acetyl]amino]-2-phenylacetic acid

Product 1

HCID 684640762-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[1-(2-methyl-1-pyrrolidin-1-ylpropan-2-yl)imidazol-4-yl]-2-phenylacetamide

Sources & evidence

ORD record
ord-ec2a9770eebe486a9742b86c3af7e078
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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