5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide → 5-amino-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide
Reaction equation
[NH2:18][c:19]1[c:20]([C:31]#[N:32])[c:21]([CH3:30])[n:22][n:23]1[CH:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1.[NH2:1][c:2]1[n:3](-[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[O:13][CH3:10])[n:11][cH:12][c:14]1[C:15]([NH2:16])=[O:17]>>[O:13]=[C:31]([c:20]1[c:19]([NH2:18])[n:23]([CH:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[n:22][c:21]1[CH3:30])[NH2:32]Participants
3
Sources & evidence
- ORD record
- ord-2eeffc3f972f4b1888ab96d6440e0c0d
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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