Acetate → N-{2-(methyloxy)-5-[3-(4-{[2-(methyloxy)phenyl]sulfonyl}-1-piperazinyl)-6-quinoxalinyl]-3-pyridinyl}cyclopropanesulfonamide

HRID 820442Notes

Reaction equation

HRID 820442 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[n:6][cH:7][c:8]([N:12]3[CH2:13][CH2:14][N:15]([S:18](=[O:19])(=[O:20])[c:21]4[c:22]([O:27][CH3:28])[cH:23][cH:24][cH:25][cH:26]4)[CH2:16][CH2:17]3)[n:9][c:10]2[cH:11]1.[Br:34][c:35]1[cH:36][c:37]([NH:43][S:44](=[O:45])(=[O:46])[CH:47]2[CH2:48][CH2:49]2)[c:38]([O:41][CH3:42])[n:39][cH:40]1.[C:50](=[O:51])([O-:52])[O-:53].[CH2:56]1[O:57][CH2:58][CH2:59][O:60][CH2:61]1.[CH3:30][C:31](=[O:32])[O-:33].[K+:29].[K+:54].[K+:55]>>[c:2]1(-[c:35]2[cH:36][c:37]([NH:43][S:44](=[O:45])(=[O:46])[CH:47]3[CH2:48][CH2:49]3)[c:38]([O:41][CH3:42])[n:39][cH:40]2)[cH:3][cH:4][c:5]2[n:6][cH:7][c:8]([N:12]3[CH2:13][CH2:14][N:15]([S:18](=[O:19])(=[O:20])[c:21]4[c:22]([O:27][CH3:28])[cH:23][cH:24][cH:25][cH:26]4)[CH2:16][CH2:17]3)[n:9][c:10]2[cH:11]1

Participants

7

Reactant 6

HCID 175AcetateHCID 813Potassium Cation3×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 57843318N-(5-Bromo-2-methoxypyridin-3-yl)cyclopropanesulfonamideHCID 685015527-Bromo-2-(4-{[2-(methyloxy)phenyl]sulfonyl}-1-piperazinyl)quinoxaline

Product 1

HCID 57843407N-{2-(methyloxy)-5-[3-(4-{[2-(methyloxy)phenyl]sulfonyl}-1-piperazinyl)-6-quinoxalinyl]-3-pyridinyl}cyclopropanesulfonamide

Sources & evidence

ORD record
ord-4d0491f4772542b692786a1244ea23e3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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