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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 820652Generated: October 28, 2026

Toluene → 2,2-Difluoro-2-phenylethylamine

https://huagongshe.com/reaction/820652

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
Reactant2,2-Difluoro-2-phenylethylamineHCID 12635529—
Reactant7-Chloro-3-(2,2,2-trifluoroacetyl)-6-trifluoromethylsulfonyloxy-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 57447747—
Reactant4-[1-(1,1,2,2,2-Pentafluoroethyl)-ethoxy]-benzylamineHCID 57655998—
Product2,2-Difluoro-2-phenylethylamineHCID 12635529—
Product7-chloro-6-{4-[1-(1,1,2,2,2-pentafluoroethyl)-ethoxy]-benzylamino}-3-(2,2,2-trifluoroacetyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepineHCID 86629682—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c657af5ffeb94b55b368e01d10916251
Source noteTest data from https://doi.org/10.1039/C8SC04228D