Pyridine → 2-(6-Cyclopropyl-5-nitro-1-oxoisoquinolin-2-yl)propyl acetate

HRID 820706Notes

Reaction equation

HRID 820706 reaction equation
[CH2:35]([Cl:36])[Cl:37].[CH3:22][C:23](=[O:24])[O:25][C:26](=[O:27])[CH3:28].[CH:1]1([c:4]2[c:5]([N+:19](=[O:20])[O-:21])[c:6]3[cH:7][cH:8][n:9]([CH:15]([CH2:16][OH:17])[CH3:18])[c:10](=[O:14])[c:11]3[cH:12][cH:13]2)[CH2:2][CH2:3]1.[cH:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1>>[CH:1]1([c:4]2[c:5]([N+:19](=[O:20])[O-:21])[c:6]3[cH:7][cH:8][n:9]([CH:15]([CH2:16][O:17][C:23]([CH3:22])=[O:24])[CH3:18])[c:10](=[O:14])[c:11]3[cH:12][cH:13]2)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 7918Acetic AnhydrideHCID 666491036-Cyclopropyl-2-(1-hydroxypropan-2-yl)-5-nitroisoquinolin-1-one

Product 1

HCID 666488872-(6-Cyclopropyl-5-nitro-1-oxoisoquinolin-2-yl)propyl acetate

Sources & evidence

ORD record
ord-9ead8821daaa4709bd6a1700c6ec9e94
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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