Ammonia → Ethyl 3-amino-l-(4-chlorophenyl)propyl(diethoxymethyl)phosphinate

HRID 820803Notes

Reaction equation

HRID 820803 reaction equation
[CH3:27][CH2:28][OH:29].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][C:10]#[N:11])[P:12]([O:13][CH2:14][CH3:15])(=[O:16])[CH:17]([O:18][CH2:19][CH3:20])[O:21][CH2:22][CH3:23])[cH:6][cH:7]1.[H:25][H:26].[NH3:24]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][CH2:10][NH2:11])[P:12]([O:13][CH2:14][CH3:15])(=[O:16])[CH:17]([O:18][CH2:19][CH3:20])[O:21][CH2:22][CH3:23])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 222AmmoniaHCID 702EthanolHCID 14362807Ethyl 1-(4-chlorophenyl)-2-cyanoethyl(diethoxymethyl)phosphinateHCID 178418361HCID 178418361, compound

Product 1

HCID 14362810Ethyl 3-amino-l-(4-chlorophenyl)propyl(diethoxymethyl)phosphinate

Sources & evidence

ORD record
ord-0c24288ed8b34d8aa87a2f5d43ebcf41
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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