N-[5-(2-amino-1-hydroxyethyl)-2-hydroxyphenyl]methanesulphonamide → Benzyl 2-[butyl-[4-[4-[[2-hydroxy-2-[4-hydroxy-3-(methanesulfonamido)phenyl]ethyl]amino]piperidin-1-yl]phenyl]sulfonylamino]acetate

HRID 820956Notes

Reaction equation

HRID 820956 reaction equation
[CH2:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[O:24][C:25]([CH2:26][N:27]([S:28](=[O:29])(=[O:30])[c:31]1[cH:32][cH:33][c:34]([N:37]2[CH2:38][CH2:39][C:40](=[O:43])[CH2:41][CH2:42]2)[cH:35][cH:36]1)[CH2:44][CH2:45][CH2:46][CH3:47])=[O:48].[NH2:1][CH2:2][CH:3]([OH:4])[c:5]1[cH:6][cH:7][c:8]([OH:16])[c:9]([NH:11][S:12](=[O:13])(=[O:14])[CH3:15])[cH:10]1>>[NH:1]([CH2:2][CH:3]([OH:4])[c:5]1[cH:6][cH:7][c:8]([OH:16])[c:9]([NH:11][S:12](=[O:13])(=[O:14])[CH3:15])[cH:10]1)[CH:40]1[CH2:39][CH2:38][N:37]([c:34]2[cH:33][cH:32][c:31]([S:28]([N:27]([CH2:26][C:25]([O:24][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)=[O:48])[CH2:44][CH2:45][CH2:46][CH3:47])(=[O:29])=[O:30])[cH:36][cH:35]2)[CH2:42][CH2:41]1

Participants

3

Reactant 2

HCID 9837752N-[5-(2-amino-1-hydroxyethyl)-2-hydroxyphenyl]methanesulphonamideHCID 69899200(Butyl-[4-(4-oxo-piperidin-1-yl)-benzenesulfonyl]-amino)-acetic acid benzyl ester

Product 1

HCID 70129329Benzyl 2-[butyl-[4-[4-[[2-hydroxy-2-[4-hydroxy-3-(methanesulfonamido)phenyl]ethyl]amino]piperidin-1-yl]phenyl]sulfonylamino]acetate

Sources & evidence

ORD record
ord-646dd5137f124cdebac73cc3528c714f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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