HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Benzoylphenylacetic acid → 2-(4-benzoylphenyl)-N-(5-(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Benzoylphenylacetic acid | HCID 11010070 | — |
| Edukt | (5-aminopyridin-3-yl)(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone | HCID 70817456 | — |
| Produkt | 2-(4-benzoylphenyl)-N-(5-(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)acetamide | HCID 70817312 | — |
Reaktionsschritte
The title compound was prepared according to the method described for Example 34 starting from (5-aminopyridin-3-yl)(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone (Preparation 95) and 2-(4-benzoylphenyl)acetic acid (JOC, 1961, 1635) to afford the title compound in 94% yield, 34 mg. LCMS (system 3): Rt=3.12 min; m/z 504 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846698B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-dceec06cfe4f4769bd26aa00fc572e30 |
| Quellennotiz | uspto-grants-2014_09 |