Potassium Cation → 2-(4-oxiranylmethylpiperazin-1-yl)-1-phenyl-1H-indole-3-carboxaldehyde

HRID 820987Notes

Reaction equation

HRID 820987 reaction equation
[Br:24][CH2:25][CH:26]1[CH2:27][O:28]1.[C:29](=[O:30])([O-:31])[O-:32].[CH3:35][C:36]#[N:37].[K+:33].[K+:34].[c:1]1(-[n:7]2[c:8]([N:18]3[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]3)[c:9]([CH:16]=[O:17])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[n:7]2[c:8]([N:18]3[CH2:19][CH2:20][N:21]([CH2:25][CH:26]4[CH2:27][O:28]4)[CH2:22][CH2:23]3)[c:9]([CH:16]=[O:17])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 18430EpibromohydrinHCID 19660Carbonate IonHCID 539968311-Phenyl-2-piperazin-1-yl-1H-indole-3-carboxaldehyde

Product 1

HCID 114852322-(4-oxiranylmethylpiperazin-1-yl)-1-phenyl-1H-indole-3-carboxaldehyde

Sources & evidence

ORD record
ord-fc8f9f77751d44269bb7ad31f2079a31
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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