4-(3-Trifluoromethyldiazirino)benzoic acid → N-{5-[(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}-4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzamide

Participants

Reaction Steps

The title compound was prepared according to the method described for Example 34 starting from (5-aminopyridin-3-yl)(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone (Preparation 95) and 4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzoic acid to afford the title compound as a white solid in 4% yield, 2 mg. LCMS (system 3): Rt=3.64 min; m/z 494 [M+H]+.

Provenance & Evidence