2-[4-(2,6-difluoro-phenoxy)-6-oxo-6H-pyridazin-1-yl]-3-phenyl-propionic acid → N-{1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1H-pyrazol-3-yl}-2-[4-(2,6-difluoro-phenoxy)-6-oxo-6H-pyridazin-1-yl]-3-phenyl-propionamide
Reaction equation
[C:28]([CH3:29])([CH3:30])([CH3:31])[Si:32]([O:33][CH2:34][CH2:35][n:36]1[n:37][c:38]([NH2:41])[cH:39][cH:40]1)([CH3:42])[CH3:43].[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][n:7][n:8]([CH:12]([C:13](=[O:14])[OH:15])[CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[c:9](=[O:11])[cH:10]2)[c:23]([F:27])[cH:24][cH:25][cH:26]1>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][n:7][n:8]([CH:12]([C:13](=[O:14])[NH:41][c:38]3[n:37][n:36]([CH2:35][CH2:34][O:33][Si:32]([C:28]([CH3:29])([CH3:30])[CH3:31])([CH3:42])[CH3:43])[cH:40][cH:39]3)[CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[c:9](=[O:11])[cH:10]2)[c:23]([F:27])[cH:24][cH:25][cH:26]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3577350d3d3749cb9ffbe09fcb4f7489
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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