Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 821100Generated: October 26, 2026

Dimethylformamide → 6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-vinyl-pyrimidine-4-carboxylic acid butyl ester

https://huagongshe.com/reaction/821100

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantButyl iodideHCID 10962—
ReactantCarbonate IonHCID 19660—
ReactantLithium ionHCID 28486—
Reactant4-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-ethenylpyrimidine-6-carboxylic acidHCID 46850912—
Product6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-vinyl-pyrimidine-4-carboxylic acid butyl esterHCID 59432087—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bc2a5b7d40e148e6a7cdd72ea26b15f4
Source noteTest data from https://doi.org/10.1039/C8SC04228D