Methyl Ethyl Ketone → tert-butyl (3RS,4RS)-4-[5-(3-benzyloxy-propoxy)-pyrimidin-2-yl]-3-hydroxy-piperidine-1-carboxylate
Reaction equation
[Br:22][CH2:23][CH2:24][CH2:25][O:26][CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[CH2:34]([C:35]([CH3:36])=[O:37])[CH3:38].[OH:1][CH:2]1[CH2:3][N:4]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:5][CH2:6][CH:7]1[c:8]1[n:9][cH:10][c:11]([OH:14])[cH:12][n:13]1>>[OH:1][CH:2]1[CH2:3][N:4]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:5][CH2:6][CH:7]1[c:8]1[n:9][cH:10][c:11]([O:14][CH2:23][CH2:24][CH2:25][O:26][CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[cH:12][n:13]1Participants
4
Sources & evidence
- ORD record
- ord-344d490c5e464242bd7bd77fc440ccbc
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…