3-(Trifluoromethyl)pyridine-2-carboxylic acid → HCID 178421639, compound

HRID 821278Notes

Reaction equation

HRID 821278 reaction equation
[F:19][C:20]([c:21]1[c:22]([C:27](=[O:28])[OH:29])[n:23][cH:24][cH:25][cH:26]1)([F:30])[F:31].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1)[C:27]([c:22]1[c:21]([C:20]([F:19])([F:30])[F:31])[cH:26][cH:25][cH:24][n:23]1)=[O:28]

Participants

3

Reactant 2

HCID 132338443-(Trifluoromethyl)pyridine-2-carboxylic acidHCID 672347104-(5-amino-2-fluorophenyl)-5,5-difluoro-4-methyl-6H-1,3-oxazin-2-amine

Product 1

HCID 178421639HCID 178421639, compound

Sources & evidence

ORD record
ord-1396c42e9a564f0eadb0453dc14818ac
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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