HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-(-)-2-Amino-1-propanol → (2R)-2-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-(-)-2-Amino-1-propanol | HCID 80308 | — |
| Reactant | (4,6-Dichloropyrimidin-5-yl)acetaldehyde | HCID 13989292 | — |
| Product | (2R)-2-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propan-1-ol | HCID 86672074 | — |
Reaction Steps
The title compound was prepared according to the method described for Preparation 1 using (4,6-dichloropyrimidin-5-yl)acetaldehyde and (R)-2-amino-1-propanol to afford the title compound as a yellow solid in 100% yield, 11.12 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846698B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-724f7da987ad489a87231b8b832ce6de |
| Source note | uspto-grants-2014_09 |