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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 82142Generated: October 25, 2026

Tert-Butylamine → 7-(tert-Butyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

https://huagongshe.com/reaction/82142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
Reactant(4,6-Dichloropyrimidin-5-yl)acetaldehydeHCID 13989292—
Product7-(tert-Butyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidineHCID 86672076—

Reaction Steps

The title compound was prepared according to the method described for Preparation 1 using (4,6-dichloropyrimidin-5-yl)acetaldehyde and tert-butylamine to afford the title compound as a yellow liquid in 77% yield, 1.61 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846698B2
Source datasetuspto-grants-2014_09
ORD IDord-410d2a6568ab42628d46249e495fea3f
Source noteuspto-grants-2014_09