Dimethyl Sulfoxide → Benzyl 3-cyanopyrrolidine-1-carboxylate

HRID 821436Notes

Reaction equation

HRID 821436 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH:12]2[CH2:13][N:14]([C:17](=[O:18])[O:19][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:15][CH2:16]2)(=[O:8])=[O:9])[cH:10][cH:11]1.[CH3:30][S:31]([CH3:32])=[O:33].[Na:27][C:28]#[N:29]>>[CH:12]1([C:28]#[N:29])[CH2:13][N:14]([C:17](=[O:18])[O:19][CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:15][CH2:16]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 15197574Benzyl 3-(tosyloxy)pyrrolidine-1-carboxylateHCID 178511850HCID 178511850, compound

Product 1

HCID 19067843Benzyl 3-cyanopyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-b5379e15079f474db88153692fcc700c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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