Methyl 5-methoxy-3-oxopentanoate → 2-[4-({[4-(2-Methoxy-ethyl)-2-(4-trifluoromethyl-phenyl)-pyrimidine-5-carbonyl]-amino}-methyl)-phenoxy]-2-methyl-propionic acid ethyl-ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][NH2:16])[cH:13][cH:14]1)=[O:17].[CH3:18][O:19][CH2:20][CH2:21][c:22]1[n:23][c:24](-[c:31]2[cH:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][cH:36]2)[n:25][cH:26][c:27]1[C:28](=[O:29])[OH:30].[CH3:41][O:42][C:43](=[O:44])[CH2:45][C:46](=[O:47])[CH2:48][CH2:49][O:50][CH3:51]>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][NH:16][C:28]([c:27]2[c:22]([CH2:21][CH2:20][O:19][CH3:18])[n:23][c:24](-[c:31]3[cH:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][cH:36]3)[n:25][cH:26]2)=[O:29])[cH:13][cH:14]1)=[O:17]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7c58b23540a14661855688a67fd7888e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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