HRID82148

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(CO[Si](C)(C)C(C)(C)C)n1cc(I)c2cncnc21

HCID70817672

未命名化合物

结构：CON(C)C(=O)c1cncc(N=C(c2ccccc2)c2ccccc2)c1

HCID86672080

未命名化合物

PRODUCTS

生成物

结构：CC(C)(CO[Si](C)(C)C(C)(C)C)n1cc(C(=O)c2cncc(N=C(c3ccccc3)c3ccccc3)c2)c2cncnc21

HCID86672081

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the method described for Preparation 24 using 7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (see Preparation 15) and 5-[(diphenylmethylene)amino]-N-methoxy-N-methylnicotinamide (see Preparation 23) to afford the title compound as a colourless gum in 56% yield, 1.49 g.

WORKUP

后处理

customThe title compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-19ba1702d8234d8bb5f6bce3230c1d2c
来源数据集: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08846698B2
来源说明: uspto-grants-2014_09

反应 SMILES

[Si:1]([O:8][CH2:9][C:10]([N:13]1[C:17]2[N:18]=[CH:19][N:20]=[CH:21][C:16]=2[C:15](I)=[CH:14]1)([CH3:12])[CH3:11])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[C:23]1([C:29](=[N:36][C:37]2[CH:38]=[N:39][CH:40]=[C:41]([CH:48]=2)[C:42](N(OC)C)=[O:43])[C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[Si:1]([O:8][CH2:9][C:10]([N:13]1[C:17]2[N:18]=[CH:19][N:20]=[CH:21][C:16]=2[C:15]([C:42]([C:41]2[CH:40]=[N:39][CH:38]=[C:37]([N:36]=[C:29]([C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH:48]=2)=[O:43])=[CH:14]1)([CH3:12])[CH3:11])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]