1-(2-Chloro-6-piperazin-1-yl-phenyl)-ethanone → 7-{4-[4-(2-Acetyl-3-chloro-phenyl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-[1,8]naphthyridin-2-one
Reaction equation
[Cl:1][c:2]1[c:3]([C:14]([CH3:15])=[O:16])[c:4]([N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1.[O:17]=[C:18]1[CH2:19][CH2:20][c:21]2[cH:22][cH:23][c:24]([O:28][CH2:29][CH2:30][CH2:31][CH:32]=[O:33])[n:25][c:26]2[NH:27]1>>[Cl:1][c:2]1[c:3]([C:14]([CH3:15])=[O:16])[c:4]([N:8]2[CH2:9][CH2:10][N:11]([CH2:32][CH2:31][CH2:30][CH2:29][O:28][c:24]3[cH:23][cH:22][c:21]4[c:26]([n:25]3)[NH:27][C:18](=[O:17])[CH2:19][CH2:20]4)[CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-34c64f94ad1942c7adeef88bb0ced417
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…