1,2,3,4-Tetrahydro-2-naphthoic acid → N-[3-cyano-4-(4-hydroxypiperidin-1-yl)phenyl]-1,2,3,4-tetrahydronaphthalene-2-carboxamide
Reaction equation
[CH2:1]1[CH:2]([C:11](=[O:12])[OH:13])[CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[NH2:14][c:15]1[cH:16][cH:17][c:18]([N:23]2[CH2:24][CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]2)[c:19]([C:20]#[N:21])[cH:22]1>>[CH2:1]1[CH:2]([C:11](=[O:13])[NH:14][c:15]2[cH:16][cH:17][c:18]([N:23]3[CH2:24][CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]3)[c:19]([C:20]#[N:21])[cH:22]2)[CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21Participants
3
Sources & evidence
- ORD record
- ord-4440c9e886a04dc7bff9d16eb1d8a8ae
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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