Methanol → tert-butyl 2-{1-amino-2-[4-(5-fluoropyridin-2-yl)phenyl]ethyl}-4-(2,2-dimethylbutyl)-1H-imidazole-1-carboxylate
Reaction equation
[CH2:1]([O:2][C:3](=[O:4])[NH:11][CH:12]([CH2:13][c:14]1[cH:15][cH:16][c:17](-[c:20]2[n:21][cH:22][c:23]([F:26])[cH:24][cH:25]2)[cH:18][cH:19]1)[c:27]1[n:28]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[cH:29][c:30]([CH2:32][C:33]([CH2:34][CH3:35])([CH3:36])[CH3:37])[n:31]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH3:47][OH:48].[H:45][H:46]>>[NH2:11][CH:12]([CH2:13][c:14]1[cH:15][cH:16][c:17](-[c:20]2[n:21][cH:22][c:23]([F:26])[cH:24][cH:25]2)[cH:18][cH:19]1)[c:27]1[n:28]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[cH:29][c:30]([CH2:32][C:33]([CH2:34][CH3:35])([CH3:36])[CH3:37])[n:31]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-4509b0161ac54dd0996005467ad1295a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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