tert-Butyl bromoacetate → HCID 70847644, compound

HRID 82171Notes

Reaction equation

HRID 82171 reaction equation
[F:1][C:2]([F:9])([F:8])[C:3]1[CH:4]=[N:5][NH:6][CH:7]=1.Br[CH2:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]>>[C:15]([O:14][C:12](=[O:13])[CH2:11][N:5]1[CH:4]=[C:3]([C:2]([F:9])([F:8])[F:1])[CH:7]=[N:6]1)([CH3:18])([CH3:17])[CH3:16]

Participants

3

Reactant 2

HCID 79177tert-Butyl bromoacetateHCID 127777954-(Trifluoromethyl)-1H-pyrazole

Product 1

HCID 70847644HCID 70847644, compound

Procedure

The title compound was prepared according to the method described for Preparation 79 using 4-(trifluoromethyl)-1H-pyrazole and tert butyl bromoacetate to afford the title compound as a yellow solid in 24% yield, 1.32 g.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-71b6755b6b1c429897d3d2f5d74f5487
Source dataset
uspto-grants-2014_09
Patent number
US08846698B2

Reaction notes

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