HRID82181

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID70817735

未命名化合物

结构：CON(C)C(=O)c1cncc(N=C(c2ccccc2)c2ccccc2)c1

HCID86672080

未命名化合物

PRODUCTS

生成物

结构：C[Si](C)(C)CCOCn1cc(C(=O)c2cncc(N=C(c3ccccc3)c3ccccc3)c2)c2cncnc21

HCID86672100

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the method described for Preparation 28 using 5-iodo-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine (Preparation 101) and 5-[(diphenylmethylene)amino]-N-methoxy-N-methylnicotinamide (Preparation 23) to afford the title compound as a yellow oil in 32% yield, 460 mg.

WORKUP

后处理

customThe title compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-db02a65302064a0cab0c04253e63cbd5
来源数据集: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08846698B2
来源说明: uspto-grants-2014_09

反应 SMILES

I[C:2]1[C:10]2[CH:9]=[N:8][CH:7]=[N:6][C:5]=2[N:4]([CH2:11][O:12][CH2:13][CH2:14][Si:15]([CH3:18])([CH3:17])[CH3:16])[CH:3]=1.[C:19]1([C:25](=[N:32][C:33]2[CH:34]=[N:35][CH:36]=[C:37]([CH:44]=2)[C:38](N(OC)C)=[O:39])[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:19]1([C:25](=[N:32][C:33]2[CH:44]=[C:37]([C:38]([C:2]3[C:10]4[CH:9]=[N:8][CH:7]=[N:6][C:5]=4[N:4]([CH2:11][O:12][CH2:13][CH2:14][Si:15]([CH3:18])([CH3:17])[CH3:16])[CH:3]=3)=[O:39])[CH:36]=[N:35][CH:34]=2)[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1