Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 82182Erstellt: 25. Oktober 2026

(4-Chlorophenyl)acetic acid → 2-(4-chlorophenyl)-N-(5-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)acetamide

https://huagongshe.com/reaction/82182

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(4-Chlorophenyl)acetic acidHCID 15880—
Edukt(5-aminopyridin-3-yl)(7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanoneHCID 70817536—
Produkt2-(4-chlorophenyl)-N-(5-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)acetamideHCID 70817591—

Reaktionsschritte

The title compound was prepared according to the method described for Examples 73-87 using (5-aminopyridin-3-yl)(7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone (Preparation 103) and 4-chlorophenylacetic acid to afford the title compound as a white solid in 66% yield, 223 mg.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08846698B2
Quelldatensatzuspto-grants-2014_09
ORD IDord-4710b3d775d3481694da288f5e57bf63
Quellennotizuspto-grants-2014_09