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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8219Generated: October 26, 2026

Thionyl Chloride → 3-Benzyl-4-bromo-butyryl chloride

https://huagongshe.com/reaction/8219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant3-Benzyl-4-bromo-butyric acidHCID 15691835—
Product3-Benzyl-4-bromo-butyryl chlorideHCID 21992929127%

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 3-benzyl-4-bromo-butyric acid (2.0 g, 7.78 mmol) and thionyl chloride (6.0 mmol) is heated to 80° C. for 2 h. The thionyl chloride is evaporated to yield 3-benzyl-4-bromo-butyryl chloride 2.1 g (99%), as a colorless liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087626B2
Source datasetuspto-grants-2006_08
ORD IDord-a73591ed459f4fe0b68338a627538e04
Source noteuspto-grants-2006_08