5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid → 5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [5-(2-hydroxy-1,1-dimethyl-ethylsulfamoyl)-4-methyl-thiazol-2-yl]-amide
Reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22](=[O:23])[OH:24])[cH:5][cH:6][c:7]1[Cl:8].[OH:25][CH2:26][C:27]([CH3:28])([CH3:29])[NH:30][S:31](=[O:32])(=[O:33])[c:34]1[c:35]([CH3:40])[n:36][c:37]([NH2:39])[s:38]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22](=[O:24])[NH:39][c:37]2[n:36][c:35]([CH3:40])[c:34]([S:31]([NH:30][C:27]([CH2:26][OH:25])([CH3:28])[CH3:29])(=[O:32])=[O:33])[s:38]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-df677d6ff8b249c4ac8e9d3d2f03a162
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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