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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 82201생성일: 2026년 10월 25일

Diisopropylethylamine → N-(5-{[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}pyridin-3-yl)-2-quinolin-7-ylacetamide

https://huagongshe.com/reaction/82201

반응식

참여 물질

역할이름HCID투입량
반응물DiisopropylethylamineHCID 81531—
반응물(Quinolin-7-yl)acetic acidHCID 18675903—
반응물(5-aminopyridin-3-yl)[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanoneHCID 70817221—
생성물N-(5-{[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}pyridin-3-yl)-2-quinolin-7-ylacetamideHCID 70817752—

반응 단계

Prepared according to the method described for Example 1 using (5-aminopyridin-3-yl)[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone (Preparation 38), and 2-quinolin-7-ylacetic acid with DIPEA as base.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08846698B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-da929026e6a64528b64e11383b334d16
출처 메모uspto-grants-2014_09