Acetic Acid → tert-butyl N-(4-amino-1-benzyl-3-hydroxy-5-phenyl-pentyl)carbamate

HRID 822092Notes

Reaction equation

HRID 822092 reaction equation
[CH2:1]([N:8]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:9]1)[CH:16]([CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[CH:24]([CH2:25][CH:26]([CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[OH:42])[c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1.[CH3:43][OH:44].[CH3:49][C:50](=[O:51])[OH:52].[CH:45]([O-:46])=[O:47].[NH4+:48]>>[NH2:8][CH:16]([CH2:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[CH:24]([CH2:25][CH:26]([CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[OH:42]

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 223AmmoniumHCID 283FormateHCID 887MethanolHCID 18759120tert-butyl N-[5-(dibenzylamino)-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate

Product 1

HCID 18758861tert-butyl N-(4-amino-1-benzyl-3-hydroxy-5-phenyl-pentyl)carbamate

Sources & evidence

ORD record
ord-1201e48e23cd4d338f45b3a9c4d06d51
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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