Ethyl bromoacetate → HCID 70847707, compound
Reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][N:6]=[CH:5]2.Br[CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14]>>[F:1][C:2]1[CH:10]=[CH:9][C:8]2[C:4](=[CH:5][N:6]([CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:7]=2)[CH:3]=1Participants
3
Procedure
The title compound was prepared according to the method described for Preparation 93 using 5-fluoro-1H-indazole and ethyl bromoacetate to afford the title compound as an off-white solid in 27% yield, 130 mg.
Workup
- customThe title compound was prepared
Sources & evidence
- ORD record
- ord-ff99cef28d064ddebb90f5cf78562b67
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08846698B2
Reaction notes
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