Ethyl bromoacetate → Ethyl (7-fluoro-1H-indazol-1-yl)acetate

HRID 82220Notes

Reaction equation

HRID 82220 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][N:8]=[CH:7]2.Br[CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14]>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:8]=[CH:7]2

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 247292477-Fluoro-1H-indazole

Product 1

HCID 70847730Ethyl (7-fluoro-1H-indazol-1-yl)acetate

Procedure

The title compound was prepared according to the method described for Preparation 93 using 7-fluoro-1H-indazole and ethyl bromoacetate to afford the title compound as an off-white solid in 41% yield, 200 mg.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-59cc0602896947c2943b678ae5c59b4c
Source dataset
uspto-grants-2014_09
Patent number
US08846698B2

Reaction notes

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