5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 5-Amino-7-[3-[3-(aminomethyl)-2-pyridinyl]-1-pyrrolidinyl]-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Reaction equation
[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([F:13])[c:11]1[F:12].[NH:22]1[CH2:23][CH:24]([c:27]2[n:28][cH:29][cH:30][cH:31][c:32]2[CH2:33][NH2:34])[CH2:25][CH2:26]1>>[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([N:22]2[CH2:23][CH:24]([c:27]3[n:28][cH:29][cH:30][cH:31][c:32]3[CH2:33][NH2:34])[CH2:25][CH2:26]2)[c:11]1[F:12]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-479cf3778be8432e812ac5a63ee56fa2
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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