alpha-Hydroxy-gamma-butyrolactone → 2,4-dihydroxy-N-[2-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]quinazolin-5-yl]oxypropyl]butanamide
Reaction equation
[NH2:1][CH2:2][CH:3]([O:4][c:5]1[c:6]2[c:7]([NH:15][c:16]3[cH:17][c:18]([CH3:30])[c:19]([O:22][c:23]4[cH:24][n:25][c:26]([CH3:29])[cH:27][cH:28]4)[cH:20][cH:21]3)[n:8][cH:9][n:10][c:11]2[cH:12][cH:13][cH:14]1)[CH3:31].[OH:32][CH:33]1[C:34](=[O:35])[O:36][CH2:37][CH2:38]1>>[NH:1]([CH2:2][CH:3]([O:4][c:5]1[c:6]2[c:7]([NH:15][c:16]3[cH:17][c:18]([CH3:30])[c:19]([O:22][c:23]4[cH:24][n:25][c:26]([CH3:29])[cH:27][cH:28]4)[cH:20][cH:21]3)[n:8][cH:9][n:10][c:11]2[cH:12][cH:13][cH:14]1)[CH3:31])[C:34]([CH:33]([OH:32])[CH2:38][CH2:37][OH:36])=[O:35]Participants
3
Sources & evidence
- ORD record
- ord-037e62fbac5d4050b7d705427a0dd80c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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