5-Methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carboxylic acid → N-[3-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methyl-1-(2-pyridyl)pyrazole-4-carboxamide
Reaction equation
[CH3:1][c:2]1[c:3]([C:13](=[O:14])[OH:15])[cH:4][n:5][n:6]1-[c:7]1[n:8][cH:9][cH:10][cH:11][cH:12]1.[NH2:16][c:17]1[cH:18][cH:19][c:20]([N:25]2[CH2:26][CH2:27][CH:28]([N:31]3[CH2:32][CH2:33][O:34][CH2:35][CH2:36]3)[CH2:29][CH2:30]2)[c:21]([C:22]#[N:23])[cH:24]1>>[CH3:1][c:2]1[c:3]([C:13](=[O:15])[NH:16][c:17]2[cH:18][cH:19][c:20]([N:25]3[CH2:26][CH2:27][CH:28]([N:31]4[CH2:32][CH2:33][O:34][CH2:35][CH2:36]4)[CH2:29][CH2:30]3)[c:21]([C:22]#[N:23])[cH:24]2)[cH:4][n:5][n:6]1-[c:7]1[n:8][cH:9][cH:10][cH:11][cH:12]1Participants
3
Sources & evidence
- ORD record
- ord-ba28f8e944a3420881a59fa282c07f09
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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