N,N-Diethyl-1,4-butanediamine → 7-(4-Diethylamino-butylamino)-3-(2,6-difluoro-3,5-dimethoxy-phenyl)-1-ethyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one
Reaction equation
[CH2:29]([CH3:30])[N:31]([CH2:32][CH2:33][CH2:34][CH2:35][NH2:36])[CH2:37][CH3:38].[F:1][c:2]1[c:3]([N:13]2[C:14](=[O:28])[N:15]([CH2:26][CH3:27])[c:16]3[n:17][c:18]([S:23]([CH3:24])=[O:25])[n:19][cH:20][c:21]3[CH2:22]2)[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]>>[F:1][c:2]1[c:3]([N:13]2[C:14](=[O:28])[N:15]([CH2:26][CH3:27])[c:16]3[n:17][c:18]([NH:36][CH2:35][CH2:34][CH2:33][CH2:32][N:31]([CH2:29][CH3:30])[CH2:37][CH3:38])[n:19][cH:20][c:21]3[CH2:22]2)[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b1cc1575c43748eda8a2f1808f2804ed
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…